The Single Wire Myograph System - 320A is ideal for studying a single vessel with a diameter of 60 μm - 3 mm. The vessel is mounted as a ring preparation by threading it over two parallel stainless steel wires and securing the wires to two supports or "jaws". One support is attached to a precision micrometer, allowing manual control of vessel circumference and stretch. The other support is attached to a force transducer for measurements of force/tension development.
The preparation is mounted in a heated 10 ml acid-resistant, stainless steel chamber, which can be covered with a lid featuring ports for rapid suction/draining, refilling and bubbling of oxygen. The base of the chamber contains a window allowing morphological observation or fluorescence measurements on an inverted microscope. Typically, the preparation is kept in the heated vessel chamber in a physiological salt solution at 37°C, bubbled with oxygen where the vessels remain viable for at least 12 hours.
The new updated Wire Interface with the finger touch screen makes it easy to setup and use. Furthermore, the new Wire Interface is prepared for the DMT Device Enabler allowing Automatic recognition of supported devices by LabChart, use of multiple devices simultaneously, correct units and ranges in LabChart channels and simultaneous recording of data into LabChart alongside a PowerLab. The DMT Device Enabler allows the Wire Myograph - 320A to stream data directly into LabChart without a Powerlab box.
√ Manually operated micropositioner for accurate tension control √ Can be easily combined with microelectrodes for membrane potential measurements √ Easily integrated into an imaging system for simultaneous force measurements and vessel wall fluorescence